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Shionogi H1 FY2026 Earnings Presentation — Shionogi & Co., Ltd. (TSE: 4507) results for the six months ended September 30, 2026, an upward revision of the FY2026 forecast, the planned acquisition of IntraBio (AQNEURSA), and financial policy. This is a Japanese-language deck (original title 2026年度 第2四半期(中間期)決算説明資料) dated October 29, 2026 and published on TDnet, the Tokyo Stock Exchange's timely disclosure system; all figures are in ¥100 million (億円) unless noted.

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आपके अपने कंटेंट से बनी स्लाइड्स के लिए इस प्रेज़ेंटेशन के कवर को स्टाइल रेफ़रेंस के रूप में इस्तेमाल करता है। या नीचे से कोई भी पेज चुनें और उसके लेआउट को रेफ़रेंस की तरह इस्तेमाल करें।

त्वरित नेविगेशन

टैग

Shionogi
Shionogi earnings presentation
塩野義製薬
決算説明資料
Japan investor presentation

स्लाइड साझा करें

विवरण

मुख्य विषय

Shionogi H1 FY2026 Earnings Presentation — Shionogi & Co., Ltd. (TSE: 4507) results for the six months ended September 30, 2026, an upward revision of the FY2026 forecast, the planned acquisition of IntraBio (AQNEURSA), and financial policy. This is a Japanese-language deck (original title 2026年度 第2四半期(中間期)決算説明資料) dated October 29, 2026 and published on TDnet, the Tokyo Stock Exchange's timely disclosure system; all figures are in ¥100 million (億円) unless noted.

मुख्य लाभ

  • •H1 FY2026 revenue of ¥350.4 billion (3,504億円), up 64.5% year on year and 103.1% of the H1 plan; core operating profit ¥115.2 billion (1,152億円), up 55.8% and 120.0% of plan
  • •EBITDA more than doubled to ¥174.6 billion (+103.4%), with Q2 operating margin rising from 31.4% in Q1 to 34.2%
  • •Full-year FY2026 forecast raised: revenue ¥720.0 billion (from ¥700.0 billion), operating profit ¥230.0 billion (from ¥220.0 billion), EBITDA ¥336.0 billion — all record highs
  • •Detailed segment tables for domestic prescription drugs, overseas subsidiaries (RADICAVA, Fetroja/Fetcroja), royalties (ViiV HIV franchise), contract manufacturing and OTC
  • •A full section on the planned ~US$2.0 billion acquisition of IntraBio and its rare-disease drug AQNEURSA (levacetylleucine) for Niemann-Pick disease type C and ataxia-telangiectasia
  • •Shareholder return plan: FY2026 dividend raised to ¥86 per share (+¥15), the 15th consecutive annual increase, with a DOE target of 4% or more

लक्षित दर्शक

  • •Equity analysts and investors covering Japanese pharmaceuticals
  • •Healthcare and biotech portfolio managers following Shionogi, ViiV Healthcare and the HIV long-acting injectable market
  • •Corporate development and BD teams studying rare-disease M&A
  • •IR and finance professionals looking for a Japanese earnings-deck reference
  • •Students and researchers of the Japanese pharma industry

उपयोग के मामले

  • •Reviewing Shionogi's first-half FY2026 performance and the revised full-year guidance
  • •Modelling royalty income from the ViiV HIV franchise (Cabenuva, Apretude, Dovato, Tivicay, Triumeq)
  • •Understanding the strategic rationale and clinical data behind the IntraBio / AQNEURSA acquisition
  • •Benchmarking how a Japanese pharma company structures a half-year results presentation (results, forecast revision, M&A, capital allocation, appendix)
  • •Using the PowerPoint version as a template for earnings, forecast-revision or acquisition-announcement slides

अद्वितीय मूल्य प्रस्ताव

  • •English page-by-page breakdown of a Japanese-only TDnet disclosure, with figures kept in the company's own ¥100 million (億円) units
  • •Covers a full earnings cycle in one deck: H1 actuals, Q1 vs Q2 bridges, forecast revision by segment and product, China restructuring, M&A and dividend policy
  • •Includes Phase 3 SARA endpoint data for AQNEURSA in NPC and A-T and the ViiV long-acting HIV pipeline (CAB+RPV every four months, VH184+VH499 twice-yearly, CAB every four months for PrEP)
  • •Available as the original PDF plus an editable PPTX conversion

स्लाइड पृष्ठ (44)

प्रत्येक स्लाइड पृष्ठ का विस्तृत दृश्य, लेआउट, मुख्य सामग्री और दृश्य तत्वों सहित।

पृष्ठ 1
Title slide

Cover: FY2026 Q2 (Interim) Financial Results Presentation

सामग्री

Title slide for Shionogi & Co., Ltd.'s FY2026 second-quarter (interim) results briefing (2026年度 第2四半期(中間期)決算 説明資料), dated October 29, 2026.

लेआउट संरचना

White background with a large left-aligned title, date and company name beneath it, and a sweeping red arc on the right ending in the circular Shionogi logo.

मुख्य दृश्य तत्व

  • •Bold black title text
  • •Large red brand arc
  • •Shionogi circular logo
पृष्ठ 2
Agenda

Agenda

सामग्री

Four sections: 01 FY2026 Q2 (interim) results overview (p.3-9); 02 FY2026 forecast revision (p.10-21); 03 Acquisition of IntraBio (p.22-29); 04 Financial policy (p.30-32).

लेआउट संरचना

Vertical numbered list with red square number badges on the left, section titles in the middle and page ranges on the right.

मुख्य दृश्य तत्व

  • •Red numbered badges 01-04
  • •Page-range references
  • •Clean white space
पृष्ठ 3
Section divider

Section Divider: FY2026 Q2 (Interim) Results Overview

सामग्री

Opens section 1, the overview of first-half FY2026 results.

लेआउट संरचना

Section divider reusing the cover's red arc and logo with a single left-aligned heading.

मुख्य दृश्य तत्व

  • •Red arc
  • •Section heading
  • •Logo
पृष्ठ 4
Financial summary table

Consolidated Results: Beat H1 Plan on Every Line

सामग्री

H1 revenue ¥3,504 (100 million yen) vs. plan ¥3,400 (103.1%) and +64.5% YoY (+¥1,374); operating profit ¥1,152 (120.0% of plan, +55.8%); profit before tax ¥1,073 (+9.9%); profit attributable to owners ¥1,195 (+44.0%); EBITDA ¥1,746 (+103.4%). Full-year plan at the time: revenue 7,000, operating profit 2,200. FY2025 figures restated after completing PPA for the JT Group pharma acquisition.

लेआउट संरचना

Headline message under a red rule, followed by a wide table: FY2026 full-year plan, H1 plan, H1 actual and achievement rate, FY2025 H1 actual, and YoY growth/change, with actual and YoY columns shaded pink.

मुख्य दृश्य तत्व

  • •Red header cells for actuals
  • •Pink-shaded highlight columns
  • •Footnotes on PPA restatement and EBITDA definition
पृष्ठ 5
Data visualization / waterfall

Growth Continued in Q2

सामग्री

Waterfall bridges from revenue to operating profit for Q1 (revenue 1,633, COGS 308, SG&A 602, R&D 318, other +107, OP 513) and Q2 (revenue 1,871, COGS 330, SG&A 605, R&D 356, other +61, OP 640). Q2 vs Q1: revenue +¥238 (100M yen, +14.5%), operating profit +¥127 (+24.8%), operating margin 31.4% → 34.2%.

लेआउट संरचना

Two side-by-side waterfall charts on the left two-thirds; a right-hand panel of three pink KPI cards with large red numbers.

मुख्य दृश्य तत्व

  • •Grey revenue bars
  • •Light-blue cost steps
  • •Red operating-profit bars
  • •Large red KPI numerals
पृष्ठ 6
Financial statement

Consolidated Statement of Profit or Loss (H1)

सामग्री

Line-by-line P&L: COGS 638 (18.2% of revenue), gross profit 2,866, SG&A + R&D 1,881 (SG&A 1,206; R&D 674 at 19.2%), other income 167, finance income/costs -80 (vs +236 a year ago), PBT 1,073. Drivers: revenue up on royalties, domestic drugs and overseas; COGS up on Torii products and one-off edaravone inventory step-up; SG&A up on amortisation of acquired intangibles (JT pharma, edaravone) and US commercial costs; other income up on ViiV equity-method profit, partly offset by a loss on the planned sale of the China generics business; finance income down as ViiV dividends are now booked against the equity-method investment, plus FX losses; net profit lifted by recognition of deferred tax assets.

लेआउट संरचना

Dense P&L table on the left with ratio percentages in small red text above values; right column of grey-headed boxes explaining key YoY drivers per line.

मुख्य दृश्य तत्व

  • •Red-bordered actual column
  • •Small red ratio annotations
  • •Explanatory callout boxes
पृष्ठ 7
Segment breakdown table

Revenue by Business

सामग्री

Domestic prescription drugs 743 (+101.7%); overseas subsidiaries/exports 950 (+210.2%), including Shionogi Inc. (US) 740 with RADICAVA 509 and Fetroja 226, Shionogi B.V. (Europe) 131 with Fetcroja 104, China 27 (-8.8%); contract manufacturing 66; OTC 78; royalty income 1,654 (+27.9%), of which HIV franchise 1,485 and other 169 (+381.8%, from former JT pharma royalties). RADICAVA US/Canada sales were US$319.0M vs US$323.7M a year earlier under Tanabe Pharma (-1.5%).

लेआउट संरचना

Segment table with indented sub-lines on the left and three driver boxes on the right; dashed footnote box beneath for RADICAVA.

मुख्य दृश्य तत्व

  • •Indented product rows
  • •Red total row
  • •Grey driver panel
पृष्ठ 8
Product sales table

Domestic Prescription Drug Revenue

सामग्री

Acute respiratory infection drugs (Xocova for COVID-19; Xofluza and Rapiacta for influenza) 49, down 44.0%; Quviviq 40 (+843%); Zurzuvae 4 (42.4% of plan); Radicut 35; Symproic 35 (+19.4%); oxycodone products 23; Torii-related products 394 (+614.4%, or +17.3% on a like-for-like basis vs ¥33.6bn under JT); other 162. Domestic total 743 (+101.7%).

लेआउट संरचना

Product-level table with plan, actual, achievement and YoY columns; two dashed footnote boxes at the bottom.

मुख्य दृश्य तत्व

  • •Red total bar
  • •Pink highlight columns
  • •Footnote boxes
पृष्ठ 9
Summary / data visualization

Q2 Results Summary

सामग्री

Growth investments made in FY2025 are paying off: H1 revenue 2,130 → 3,504 (+64.5%), operating profit 740 → 1,152 (+55.8%), EBITDA 858 → 1,746 (+103.4%).

लेआउट संरचना

Three paired bar charts (FY2025 H1 vs FY2026 H1) with dotted red growth arrows; the revenue bars are stacked by business.

मुख्य दृश्य तत्व

  • •Grey vs red bars
  • •Dotted growth arrows
  • •Stacked revenue composition
पृष्ठ 10
Section divider

Section Divider: FY2026 Forecast Revision

सामग्री

Opens section 2 on the revised full-year forecast.

लेआउट संरचना

Red-arc section divider with a single heading.

मुख्य दृश्य तत्व

  • •Red arc
  • •Heading
  • •Logo
पृष्ठ 11
Text / explanation

About the Forecast Revision

सामग्री

Revenue and all profit lines raised. Revenue: domestic Quviviq and Torii products up, acute respiratory drugs cut for the H1 shortfall (H2 unchanged), Zurzuvae slower; overseas Shionogi Inc./B.V. up, AQNEURSA revenue to be booked after the IntraBio deal closes, cefiderocol solid; HIV royalties from ViiV strong. Costs: COGS up for inventory step-up after closing; SG&A up for intangible amortisation and AQNEURSA launch, with cost management continued; R&D reprioritised across the integrated pipeline. Other income up on ViiV equity-method profit, offset by the China generics divestment loss.

लेआउट संरचना

Four grey-headed panels (Revenue, COGS, Expenses, Other income/expense) with bulleted text; red marks positive and blue negative factors.

मुख्य दृश्य तत्व

  • •Grey panel headers
  • •Red and blue coded subheadings
  • •Hyperlinked press-release footnote
पृष्ठ 12
Guidance table

Consolidated Forecast: Record Highs

सामग्री

FY2026 forecast revised: revenue 7,000 → 7,200 (+200), operating profit 2,200 → 2,300 (+100), PBT 2,200 → 2,205, profit attributable to owners 2,100 → 2,125, EBITDA 3,150 → 3,360 (+210). Versus FY2025 actual: revenue +44.1% (4,997), operating profit +35.1% (1,703), net profit +1.6% (2,092), EBITDA +79.0%. Revenue, operating profit and net profit all at record levels.

लेआउट संरचना

Table comparing original vs revised forecast and FY2025 actual, with red-highlighted revised columns.

मुख्य दृश्य तत्व

  • •Red header cells
  • •Pink-shaded revised columns
  • •EBITDA footnote
पृष्ठ 13
Financial forecast table

Consolidated P&L Forecast (Full Year and H2)

सामग्री

Revised full year: COGS 1,250 (17.4%), gross profit 5,950, SG&A 2,650 (+250), R&D 1,400 (-150), other income 400, operating profit 2,300 (31.9% margin), finance costs -95. Implied H2: revenue 3,696, operating profit 1,148 (-92 vs original H2), net profit 930.

लेआउट संरचना

Wide P&L grid with full-year and H2 blocks (original, revised, change) plus FY2025 actual and YoY columns; ratios in red.

मुख्य दृश्य तत्व

  • •Two forecast blocks
  • •Red-bordered revised columns
  • •Ratio annotations
पृष्ठ 14
Segment forecast table

Revenue Forecast by Business

सामग्री

Domestic 1,786 → 1,720 (-67); overseas 1,752 → 1,913 (+160), of which Shionogi Inc. 1,505 (RADICAVA 1,003), Shionogi B.V. 253, China 52; contract manufacturing 133; OTC 173; royalties 3,106 → 3,235 (+129), HIV franchise 2,890. Total 7,200, +44.1% vs FY2025.

लेआउट संरचना

Segment forecast table with original/revised/change for full year and H2, FY2025 actual and YoY.

मुख्य दृश्य तत्व

  • •Red revised columns
  • •Indented subsidiaries
  • •Red total row
पृष्ठ 15
Product forecast table

Domestic Prescription Drug Forecast

सामग्री

Acute respiratory infection drugs cut 416 → 302 (-113); Quviviq raised 67 → 89; Zurzuvae cut 40 → 10; Radicut 70 unchanged; Symproic 70; oxycodone 46; Torii products 792 (+16); other 340. Domestic total 1,720, +39.3% vs FY2025.

लेआउट संरचना

Product-level forecast table mirroring page 14 with a footnote box listing the respiratory drugs.

मुख्य दृश्य तत्व

  • •Red total row
  • •Negative revisions shown with triangle markers
  • •Footnote box
पृष्ठ 16
Strategy / growth drivers

Growth of the Domestic Business

सामग्री

Strong growth in QOL (quality-of-life) disease areas expands the domestic earnings base to a forecast ¥172.0bn. Infectious diseases: continued preparation for respiratory seasons with Xocova, Xofluza and Rapiacta. QOL: Quviviq (insomnia) adoption rising in psychiatry and internal medicine; psychiatric presence extended to Zurzuvae (depression); co-promotion of Torii's Corectim and Vtama; Radicut ALS early-diagnosis awareness.

लेआउट संरचना

Stacked bar chart (FY2024, FY2025, FY2026 forecast) on the left; right side panels for infectious and QOL franchises with product boxes and process icons.

मुख्य दृश्य तत्व

  • •Green and blue stacked bars
  • •Product name boxes
  • •Hospital and brain icons
पृष्ठ 17
Strategy / growth drivers

Further Growth of the Overseas Business

सामग्री

Overseas forecast ¥191.3bn, driven by infectious disease and a RADICAVA-anchored rare-disease franchise. Rare disease: RADICAVA early-diagnosis and persistence support; AQNEURSA (after closing) for NPC and A-T. Infectious disease: cefiderocol growth in the US/EU and new indications/regions; ensitrelvir US expansion and EU approval.

लेआउट संरचना

Stacked bar chart (infectious, rare disease, other) on the left; blue rare-disease and green infectious-disease panels on the right.

मुख्य दृश्य तत्व

  • •Dotted stacked bars
  • •Blue and green section headers
  • •Product cards
पृष्ठ 18
Timeline

History of the China Business

सामग्री

2011: entered China by acquiring C&O Pharmaceutical (network to ~300,000 clinics, hospitals and pharmacies). 2020: Ping An Shionogi JV formed with Ping An Insurance (51/49), cefiderocol filing and early access, AI drug discovery. 2025 onward: acquired Ping An's 49% stakes, making the Shanghai and Hong Kong JVs wholly owned (Shionogi China) and shifting to a new-drug-centred model.

लेआउट संरचना

Three-column timeline with grey headers, bullets, and a row of chevron arrows progressing from light pink to red.

मुख्य दृश्य तत्व

  • •Three-stage chevrons
  • •Dashed column dividers
  • •Press-release links
पृष्ठ 19
Restructuring / org chart

Restructuring the China Business

सामग्री

Due to price pressure from policy changes and intensifying competition, China revenue fell about 50% over three years; Shionogi will sell the generics subsidiaries (a Shenzhen sales company and a Nanjing development/manufacturing company), recording a loss of about ¥7.2 billion (72億円) after reassessing asset values.

लेआउट संरचना

Left: bullet points and a declining bar chart FY2020-FY2025 with a red arrow and '~50% down in 3 years' badge. Right: org chart of the two subsidiaries to be divested inside a dashed box.

मुख्य दृश्य तत्व

  • •Grey bar chart with red trend arrow
  • •Red circular callout
  • •Dashed divestment box
पृष्ठ 20
Strategy

China Growth Strategy

सामग्री

Aim to build a new-drug business in China that contributes to global growth. Two pillars: (1) continued new-drug launches — approved cefiderocol and naldemedine (sales agreement with Chia Tai Tianqing), pipeline olorofim (invasive aspergillosis) whose Phase 3 met its primary endpoint; (2) strengthening the business base with stable earnings and product-specific approaches.

लेआउट संरचना

Left column with two numbered pillars and product boxes; right side a blue gradient background with a large red upward arrow and slogan text.

मुख्य दृश्य तत्व

  • •Numbered blue circles
  • •Approved vs pipeline boxes
  • •Large red growth arrow
पृष्ठ 21
Data visualization / KPI

Long-Acting Injectables Supporting the HIV Franchise

सामग्री

ViiV's long-acting injectable (LAI) sales grew +£144M (+30%) YoY at constant exchange rates. CY2026 Q3: Cabenuva (cabotegravir + rilpivirine, treatment) £478M, +35%; Apretude (cabotegravir, PrEP) £143M, +21%.

लेआउट संरचना

Quarterly stacked bar chart CY2021-CY2026 Q3 in £M on the left; two rounded KPI cards with product logos on the right.

मुख्य दृश्य तत्व

  • •Stacked quarterly bars
  • •Cabenuva and Apretude logos
  • •Large red growth numbers
पृष्ठ 22
Section divider

Section Divider: Acquisition of IntraBio

सामग्री

Opens section 3. Closing is subject to antitrust waiting periods and regulatory clearances; expected closing November-December 2026.

लेआउट संरचना

Red-arc divider with heading and a short legal note beneath.

मुख्य दृश्य तत्व

  • •Red arc
  • •Heading
  • •Closing-conditions note
पृष्ठ 23
Strategic rationale

Purpose of the IntraBio Acquisition

सामग्री

Accelerate rare-disease expansion by acquiring a promising commercial asset and expertise: (1) further expand the overseas business with a marketed product, leveraging the US RADICAVA infrastructure; (2) strengthen rare-disease development via IntraBio's network with patient groups, KOLs and researchers.

लेआउट संरचना

Two equal white cards with red circular icons, joined by a large grey multiplication sign.

मुख्य दृश्य तत्व

  • •Globe and hand-plant icons
  • •Red emphasis headlines
  • •Multiplication sign
पृष्ठ 24
Company profile

About IntraBio

सामग्री

IntraBio Inc. (private), founded November 2015, headquartered in Texas, ~60 employees, revenue about US$68 million (FY ended December 2025, AQNEURSA sales). Lead product AQNEURSA (levacetylleucine), an oral small molecule improving lysosomal function and energy metabolism, approved for neurological manifestations of NPC (US/EU) and ataxia in A-T (US). Strong partnerships with NPC and A-T patient groups.

लेआउट संरचना

Company-profile table on the left; product card with AQNEURSA logo and indications on the upper right; red partnership box below.

मुख्य दृश्य तत्व

  • •Numbered section headers
  • •AQNEURSA logo
  • •Indication callout
पृष्ठ 25
Disease overview

Niemann-Pick Disease Type C (NPC)

सामग्री

Rare inherited lysosomal disorder caused by NPC1/NPC2 mutations that lead to lipid accumulation; symptoms include ataxia, cognitive decline, eye-movement disorder and hepatosplenomegaly. Incidence about 1 in 100,000; about 400 diagnosed patients in the US and 500 in the EU5. Existing therapies mainly slow progression.

लेआउट संरचना

Left: lysosome illustration with membrane-transport diagram and four symptom tiles. Right: three stacked KPI cards (incidence, diagnosed patients, treatment landscape).

मुख्य दृश्य तत्व

  • •Cell diagram
  • •Symptom tiles
  • •Large KPI figures
पृष्ठ 26
Disease overview

Ataxia-Telangiectasia (A-T)

सामग्री

Serious rare genetic disease from ATM mutations impairing DNA repair, affecting the nervous, immune and respiratory systems; symptoms include ataxia, immunodeficiency, recurrent infections, lung disease, higher cancer risk and telangiectasia. Incidence about 1 in 40,000-100,000; about 1,500 diagnosed patients in the US and 800 in the EU5. AQNEURSA is the first approved therapy.

लेआउट संरचना

Same template as page 25: DNA/cell illustration with six symptom tiles on the left, three KPI cards on the right.

मुख्य दृश्य तत्व

  • •DNA damage illustration
  • •Symptom grid
  • •KPI cards
पृष्ठ 27
Clinical data

Phase 3 Results (NPC / A-T)

सामग्री

Global Phase 3 trials IB1001-301 (NPC, NCT05163288) and IB1001-303 (A-T, NCT06673056) in children and adults, 12 weeks, primary endpoint improvement in SARA score. NPC: 1.97 vs 0.60 placebo (N=59/58, p<0.001). A-T: 1.92 vs 0.14 placebo (N=69/72, p<0.001). No drug-related serious adverse events.

लेआउट संरचना

Top band with trial design; lower-left SARA explainer with daily-function bubbles; lower-right efficacy and safety text plus two bar charts.

मुख्य दृश्य तत्व

  • •Red vs grey bar charts
  • •p-value brackets
  • •Function bubbles (walk, stand, sit, speak)
पृष्ठ 28
Timeline / roadmap

AQNEURSA Development Status

सामग्री

NPC: Phase 3 started June 2022; US filing Jan 2024, approval and launch Sept 2024; EU filing June 2024, approval Jan 2026. A-T: Phase 3 started March 2025; US filing March 2026, approval and label expansion Sept 2026; EU filing June 2026.

लेआउट संरचना

Two horizontal swim-lane timelines (blue for NPC, red for A-T) with milestones for Phase 3 start, filing, approval and launch.

मुख्य दृश्य तत्व

  • •Blue and red swim lanes
  • •Circle milestones
  • •Square launch markers
पृष्ठ 29
Strategy

Global Rare-Disease Expansion (Post-Closing)

सामग्री

US: combine IntraBio's network (patient groups, specialist centres, KOLs) with RADICAVA's patient-support infrastructure to accelerate AQNEURSA uptake. Europe: use the newly approved rare-disease drug to build a rare-disease organisation (talent, patient-group ties) and establish presence.

लेआउट संरचना

Two columns (US in pink, Europe in red) with icon rows, downward chevrons and outcome boxes with red text.

मुख्य दृश्य तत्व

  • •Network, hospital and badge icons
  • •Chevron arrows
  • •Red-outlined outcome boxes
पृष्ठ 30
Section divider

Section Divider: Financial Policy

सामग्री

Opens section 4 on financial policy.

लेआउट संरचना

Red-arc divider with heading.

मुख्य दृश्य तत्व

  • •Red arc
  • •Heading
  • •Logo
पृष्ठ 31
Capital allocation

FY2026 Cash Allocation

सामग्री

Cash available ¥940.0bn (9,400億円): operating cash flow before R&D ¥480.0bn plus carried-over cash ~¥460.0bn. Planned uses: R&D ¥155.0bn, business/capital investment ¥720.0bn (with flexibility for higher dividends, buybacks or debt repayment) and dividends ¥65.0bn. H1 progress: R&D ~¥68.0bn, investments ~¥335.0bn (assuming the US$2.0bn IntraBio share purchase), dividends ¥32.3bn. Policies: investment judged against cost of capital; return quickly to a net cash position; DOE target of 4% or more and opportunistic buybacks.

लेआउट संरचना

Cash-in vs cash-out block diagram on the left, H1 progress column in the centre, policy panels on the right.

मुख्य दृश्य तत्व

  • •Grey cash-in block
  • •Pink and red cash-out blocks
  • •Dashed arrow to dividends
पृष्ठ 32
Shareholder returns / data visualization

Further Expansion of Shareholder Returns

सामग्री

Record dividend increase: interim raised by ¥2 and year-end by ¥8 versus prior guidance, for an annual dividend of ¥86 per share (interim ¥40, year-end ¥46), up ¥15 from ¥71 in FY2025 — the 15th consecutive increase. DOE forecast 4.2%. History table shows buybacks, cancellations, ROE and DOE from FY2012 (split-adjusted for the October 2024 3-for-1 stock split).

लेआउट संरचना

Bullet points top-left; bar chart of dividends per share FY2012-FY2026 with the FY2026 bar in pink/red; data table beneath with buybacks, ROE and DOE.

मुख्य दृश्य तत्व

  • •Rising grey bars
  • •Highlighted red FY2026 bar
  • •Historical data table
पृष्ठ 33
Section divider

Section Divider: Appendix

सामग्री

Opens the appendix.

लेआउट संरचना

Red-arc divider with 'Appendix' heading.

मुख्य दृश्य तत्व

  • •Red arc
  • •Heading
पृष्ठ 34
Appendix table

FY2026 Exchange Rates

सामग्री

Average-rate assumptions: USD ¥153.0 (May 12) → ¥159.0 (Oct 29), actual Apr-Sep ¥159.49; GBP ¥205.0 → ¥213.4, actual ¥214.16; EUR ¥184.0 → ¥184.4, actual ¥184.44.

लेआउट संरचना

Single centred table with grey header and red-highlighted actual column.

मुख्य दृश्य तत्व

  • •Grey header band
  • •Red actual column
  • •Pink shading
पृष्ठ 35
Appendix / reconciliation

Revision of Q1 Results

सामग्री

Q1 results were restated to reflect completed edaravone PPA and provisional ViiV PPA: amortisation of product intangibles reduced by 9 (158 → 150), other income cut by 165 (272 → 107), so operating profit falls from 669 to 513, PBT from 737 to 581 and net profit from 977 to 818. Revenue unchanged at 1,633.

लेआउट संरचना

Reconciliation table with pre-restatement, change and restated columns plus a description column.

मुख्य दृश्य तत्व

  • •Red-bordered restated column
  • •Pink rows for changed lines
  • •Explanation text
पृष्ठ 36
Data visualization / waterfall

Bridge from Operating Profit to Quarterly Net Profit

सामग्री

Q1 (Apr-Jun): operating profit 513 + finance income 68 + tax benefit 237 (deferred tax asset recognition) = net profit 818 (+306). Q2 (Jul-Sep): operating profit 640 - finance costs 148 - income tax 114 = net profit 377 (-262), with FX weighing on finance results.

लेआउट संरचना

Two waterfall charts side by side, red increments for Q1 and blue decrements for Q2, with central callout badges.

मुख्य दृश्य तत्व

  • •Red and blue waterfall steps
  • •Rounded callout badges
  • •Grey totals
पृष्ठ 37
Appendix table

Torii-Related Product Revenue (H1)

सामग्री

Dermatology 116 (+9.5%): Corectim 53 (+15.2%), Vtama 12 (-21.4%); allergen and other 278 (+20.8%). Torii-related total 394, +17.3% vs 336 under JT Group in the prior-year period.

लेआउट संरचना

Compact product table with plan, actual, achievement and YoY columns.

मुख्य दृश्य तत्व

  • •Red header cells
  • •Red total row
  • •Footnotes on comparison basis
पृष्ठ 38
Appendix table

Torii-Related Product Forecast Revision

सामग्री

Full-year Torii-related revenue raised 776 → 792: dermatology 225 (Corectim raised to 105, Vtama cut to 28), allergen and other 567 (+21). +15.4% vs FY2025 pro forma 686.

लेआउट संरचना

Forecast table with full-year and H2 original/revised blocks plus FY2025 and YoY.

मुख्य दृश्य तत्व

  • •Red revised columns
  • •Triangle negative markers
  • •Red total row
पृष्ठ 39
Product portfolio table

ViiV's HIV Treatment and Prevention Lineup

सामग्री

2025 sales: Cabenuva (CAB+RPV LAI, IM every 2 months, treatment) £1,402M; Apretude (CAB LAI, PrEP) £439M; Dovato (DTG+3TC oral) £2,678M; Juluca (DTG+RPV oral) £656M; Tivicay (DTG) £1,323M; Triumeq (DTG+ABC+3TC) £991M.

लेआउट संरचना

Colour-banded product table (blue LAIs, red two-drug orals, yellow single/three-drug) with formulation, compound, route, frequency, indication and sales columns.

मुख्य दृश्य तत्व

  • •Colour-coded product bands
  • •Bold product names
  • •£M sales column
पृष्ठ 40
R&D / competitive advantage

Creating an Integrase Inhibitor LAI: Cabenuva (6 Doses a Year)

सामग्री

No competing integrase-inhibitor LAI expected to be approved before 2030. Shionogi/ViiV combined proof that two-drug oral regimens work (Dovato, Juluca) with a compound that sustains blood levels. Cabotegravir is the world's only approved integrase-inhibitor LAI: dolutegravir-like potency and resistance barrier, dosing every two months (SOLAR study), and patent protection to 2040 via additional patents.

लेआउट संरचना

Left grey panel with two overlapping circles and a multiplication sign; arrow to right panel with three icon-led strength boxes.

मुख्य दृश्य तत्व

  • •Pill and molecule icons
  • •Syringe and shield icons
  • •Red headline
पृष्ठ 41
Pipeline

Treatment Dosed Three Times a Year (CAB+RPV LAI)

सामग्री

Extending Cabenuva's dosing from six to three times a year: reliability from Cabenuva clinical experience; treatment days cut from 365 (daily oral) to 3; about 2x clinic capacity; capture switching from orals and competitors. Phase 3 CUATRO study started June 2026; approval targeted CY2028; aim to extend protection to 2047 (cabotegravir compound patent expires 2031).

लेआउट संरचना

Regimen card on the left feeding four numbered benefit tiles; schedule and patent-strategy boxes below.

मुख्य दृश्य तत्व

  • •Roman-numeral tiles
  • •365 → 3 callout
  • •Red schedule text
पृष्ठ 42
Pipeline

Treatment Dosed Twice a Year (VH184 + VH499)

सामग्री

Two-drug regimen of S-365598 (VH184, third-generation integrase inhibitor with a distinct resistance profile) and VH499 (capsid inhibitor with low drug-drug interaction risk), aiming for six-month dosing for the broadest patient population. VH184 INNOVATE Phase 2b ongoing; VH499 Phase 2b CINERGY study to start CY2026 H2; Phase 3 start CY2028. Compound patents expire in the 2040s, with protection targeted to at least 2047.

लेआउट संरचना

Same template as page 41: regimen card, four numbered tiles, schedule and patent boxes.

मुख्य दृश्य तत्व

  • •Numbered tiles
  • •Regimen card
  • •Patent strategy box
पृष्ठ 43
Pipeline

Prevention Dosed Three Times a Year (CAB)

सामग्री

Single-agent cabotegravir for PrEP every four months: reliability proven by Apretude (over 99% efficacy and 4+ years of real-world evidence), one IM injection per visit, schedule aligned with routine STI testing, favourable injection-site reaction and DDI profile. EXTEND 4M pivotal data in CY2026 H2; approval targeted CY2027; protection sought to 2045.

लेआउट संरचना

Same four-tile pipeline template with schedule and patent boxes.

मुख्य दृश्य तत्व

  • •Single-agent card
  • •Four benefit tiles
  • •Red schedule text
पृष्ठ 44
Disclaimer

Forward-Looking Statements

सामग्री

Standard disclaimer: the deck contains forward-looking statements subject to risks including economic conditions, FX, clinical and regulatory outcomes, healthcare reforms and manufacturing; product information is not advertising or medical advice; the deck is not a solicitation to invest.

लेआउट संरचना

Full-width bulleted text slide.

मुख्य दृश्य तत्व

  • •Bulleted legal text
  • •Logo footer

अक्सर पूछे जाने वाले प्रश्न

इस स्लाइड और अंतर्निहित प्रस्तुति सामग्री के बारे में सामान्य प्रश्न।

What does the Shionogi H1 FY2026 Earnings Presentation cover?

It covers Shionogi's results for April-September 2026 (the first half of FY2026, which runs April 2026 to March 2027), the upward revision of full-year guidance, the planned acquisition of IntraBio and its rare-disease drug AQNEURSA, the China restructuring, the ViiV long-acting HIV pipeline, and cash allocation and dividend policy, across 44 slides.

Is this deck in Japanese, and where was it originally published?

Yes. The original is a Japanese-language results briefing deck (決算説明資料, titled 2026年度 第2四半期(中間期)決算説明資料) released on October 29, 2026 via TDnet, the Tokyo Stock Exchange's timely disclosure system, under securities code 4507. The page-by-page summary on this page is written in English, with amounts kept in the company's ¥100 million (億円) units.

What were Shionogi's key numbers for H1 FY2026?

Revenue was ¥350.4 billion (+64.5% YoY), operating profit ¥115.2 billion (+55.8%), profit attributable to owners ¥119.5 billion (+44.0%) and EBITDA ¥174.6 billion (+103.4%). Royalty income, mostly from ViiV's HIV franchise, was ¥165.4 billion.

How did Shionogi revise its FY2026 forecast?

Full-year revenue was raised from ¥700.0 billion to ¥720.0 billion, operating profit from ¥220.0 billion to ¥230.0 billion and EBITDA from ¥315.0 billion to ¥336.0 billion. The annual dividend forecast rose to ¥86 per share, up ¥15 and the 15th consecutive increase.

Why is Shionogi acquiring IntraBio?

IntraBio markets AQNEURSA (levacetylleucine) for Niemann-Pick disease type C and ataxia-telangiectasia. Shionogi plans to use its US RADICAVA infrastructure to grow AQNEURSA and to build a rare-disease presence in Europe. The deal assumes a share purchase of about US$2.0 billion and is expected to close in November-December 2026.

Can I download this presentation as PowerPoint?

Yes. The page offers the original PDF and an editable PPTX converted from it. Because the source is Japanese, the slide text in both files is in Japanese; the conversion may need minor layout touch-ups.

Who is this presentation useful for?

Investors and analysts covering Japanese pharma or the HIV long-acting injectable market, BD teams studying rare-disease acquisitions, and IR professionals who want a well-structured example of a half-year results deck with a forecast revision and an M&A section.

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